Journal of clinical anesthesia
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We report two cases of overdoses of intramuscular midazolam used as a premedication. Both cases had no resedation or complications, but the accidents happened as a result of a resident and nurse's lack of experience with midazolam. The intramuscular doses, given at four times the normal quantity, fortunately caused no harm in our cases. However, the situations suggest that we should carefully check the dosage and review the correct procedures, even when using a drug that is considered to be familiar with most practitioners.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of the effects of droperidol and the combination of droperidol and ondansetron on postoperative nausea and vomiting for patients undergoing laparoscopic cholecystectomy.
To compare the prophylactic antiemetic efficacy of the combination of ondansetron and droperidol with that of droperidol alone in patients undergoing elective laparoscopic cholecystectomy. ⋯ Patients who received the combination of droperidol and ondansetron experienced less severe nausea compared with patients who received droperidol alone.
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Randomized Controlled Trial Clinical Trial
Effect of maintenance bolus on the recovery profile of a short-acting nondepolarizing muscle relaxant.
To evaluate the effect of different maintenance boluses of a short-acting nondepolarizing neuromuscular blocking drug on its spontaneous recovery profile during anesthesia. ⋯ Spontaneous recovery of the T(1) to 25% of the baseline value occurred 6 to 10 minutes after a maintenance bolus dose of rapacuronium 0.25 to 0.75 mg x kg(-1) i.v. However, recovery to a TOF>0.7 required 44 to 66 minutes during desflurane anesthesia.
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Randomized Controlled Trial Clinical Trial
Patient-controlled bupivacaine wound instillation following cesarean section: the lack of efficacy of adjuvant ketamine.
To assess the analgesic efficacy of ketamine when administered as an adjuvant to bupivacaine for patient-controlled wound instillation following cesarean section. ⋯ Adjuvant local ketamine does not enhance bupivacaine-induced wound instillation following cesarean section.
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To evaluate whether preoperative blood volume and postoperative blood loss influence blood transfusion in females and males undergoing coronary artery bypass graft (CABG) surgery. ⋯ The greater need for blood transfusion in females than in males during CABG is primarily attributable to significantly lower preoperative total blood volume and RBC volume in females.