Current opinion in anaesthesiology
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Positive inotropic agents are widely used in the management of the critical ill patient presenting with low cardiac output state. Different inotropic agents are available, and different effects on hemodynamic endpoints may be recognized, but data on relevant clinical endpoints are scarce. A growing body of literature suggests that overuse of inotropes may have detrimental effects on cardiomyocytes, resulting in an increased risk of morbidity and mortality. The present review will summarize recent literature, focusing on outcome studies among adult patients related to use of inotropes in different clinical settings. ⋯ A 'less is more' approach may show to be appropriate when relating to routine use of inotropes. Inotropic therapy should be restricted to patients with heart failure and clinical signs of end-organ hypoperfusion.
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The mean age of patients presenting for thoracic surgery is rising steadily, associated with an increased demand for thoracic surgical treatments by geriatric patients. With increasing age, physiologic changes and comorbidities have to be considered. Thoracic anesthesia for elderly patients requires greater specific knowledge. ⋯ Considering key points of physiology and pharmacology can help to provide best possible care for the increasing number of elderly patients in thoracic surgery. Management of geriatric patients in thoracic surgery offer opportunities for anaesthetic interventions including protective ventilation, use of different anesthetics, anaesthesia monitoring, fluid management and pain therapy.
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Curr Opin Anaesthesiol · Feb 2015
ReviewPreventive and therapeutic noninvasive ventilation in cardiovascular surgery.
Postoperative pulmonary complications are common after cardiac and vascular surgery, and they are associated with a marked worsening in hospital survival and length of stay. Noninvasive ventilation (NIV) has been successfully applied in the prevention and treatment of postoperative acute respiratory failure (ARF), including the cardiovascular setting. ⋯ NIV seems effective when applied to treat postoperative ARF. Its role as a preventive tool is still controversial, and probably should be limited to high-risk patients. Promising findings were reported for NIV application in pediatric patients and in ancillary procedures. So far, a cautious approach should be applied, as NIV failure is associated with poor outcomes if not quickly detected.
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Curr Opin Anaesthesiol · Feb 2015
ReviewPerioperative myocardial perfusion: an anesthesiologists' concern?
General anesthesia has only small effects on myocardial perfusion in healthy patients.
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