Gynecologic oncology
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Gynecologic oncology · Nov 2007
Multicenter Study Comparative StudyThe role of multi-modality adjuvant chemotherapy and radiation in women with advanced stage endometrial cancer.
: The optimal adjuvant therapy for women with stages III and IV endometrial cancer following surgical staging and cytoreductive surgery is controversial. We sought to determine the outcome of patients with advanced stage endometrial cancer treated with postoperative chemotherapy+/-radiation to determine whether there was an advantage to combining treatment modalities. ⋯ : Combined adjuvant chemotherapy and radiation was associated with improved survival in patients with advanced stage disease compared to either modality alone. Future clinical trials are needed to prospectively evaluate multi-modality adjuvant therapy in women with advanced staged endometrial cancer to determine the appropriate sequencing and types of chemotherapy and radiation.
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Gynecologic oncology · Nov 2007
Comparative StudyManagement of platinum-sensitive recurrent ovarian cancer: a cost-effectiveness analysis.
We wished to compare the cost-effectiveness of three chemotherapy regimens for treatment of recurrent platinum-sensitive ovarian cancer. ⋯ PC appears to be relatively cost-effective compared to C for the treatment of recurrent platinum-sensitive ovarian cancer. GC appears to be less cost-effective compared to PC, with an ICER ten times higher.
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Gynecologic oncology · Nov 2007
Role of systematic lymphadenectomy and adjuvant therapy in stage I uterine papillary serous carcinoma.
To assess surgical staging with systematic lymphadenectomy (LND) and adjuvant therapy in patients with stage I uterine papillary serous carcinoma (UPSC). ⋯ Observation is an option for patients with stage IA UPSC confirmed by systematic LND. Patients with comprehensively staged IB and IC UPSC are candidates for chemotherapy and vaginal brachytherapy to prevent HPR and VR.
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Gynecologic oncology · Nov 2007
Editorial Historical ArticleThe Society of Gynecologic Oncologists: yesterday, today and tomorrow.