Urology
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Randomized Controlled Trial
Diclofenac suppository administration in conjunction with lidocaine gel during transrectal ultrasound-guided prostate biopsy: prospective, randomized, placebo-controlled study.
To evaluate the additional analgesic efficacy of the rectal administration of diclofenac suppository compared with placebo in patients undergoing transrectal ultrasound-guided prostate biopsy. ⋯ Intrarectal diclofenac suppository administration is a simple, safe, and effective procedure to reduce pain and improve patients' tolerance of transrectal ultrasound-guided prostate biopsy. We recommend intrarectal diclofenac suppository administration, together with intrarectally administered lidocaine gel, in men undergoing transrectal ultrasound-guided prostate biopsy.
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Randomized Controlled Trial Clinical Trial
Efficacy of continuous local anesthetic infusion for postoperative pain after radical retropubic prostatectomy.
To determine whether a subfascial continuous infusion of local anesthetic in patients undergoing radical retropubic prostatectomy would result in a reduction in postoperative opioid requirements and an improvement in pain scores. ⋯ Continuous subfascial infusion of local anesthetic did not result in a postoperative reduction in opioid requirements or an improvement in pain scores in patients undergoing radical retropubic prostatectomy.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study.
To introduce two forms of anesthesia and compare them with standard local anesthesia techniques. ⋯ The use of 40% DMSO with lidocaine instilled into the rectal vault for 10 minutes avoids any need for injection and is capable of decreasing the discomfort or pain experienced during probe insertion and prostate biopsy comparable to the perianal and periprostatic protocols.
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Randomized Controlled Trial Clinical Trial
Tranexamic acid in control of primary hemorrhage during transurethral prostatectomy.
To determine whether short-term treatment of patients about to undergo transurethral resection of the prostate (TURP) with tranexamic acid (TXA) would be beneficial in reducing the associated blood loss. ⋯ Short-term TXA treatment is effective in reducing the operative blood loss associated with TURP.
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Randomized Controlled Trial Comparative Study Clinical Trial
Unilateral pudendal nerve blockade for relief of all pain during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study.
To investigate the efficacy of unilateral pudendal nerve block for the relief of all pain during transrectal ultrasound (TRUS)-guided prostate biopsy. TRUS-guided prostate biopsy is the standard procedure to diagnose or rule out prostate cancer. The pain, attributed to ultrasound probe insertion and the needle punctures into the prostate, inflicted by TRUS-guided prostate biopsy limits its effectiveness. ⋯ Unilateral pudendal nerve blockade was effective in reducing the pain at both biopsy and probe manipulation in our study.