Urology
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To examine the outcomes in patients with and without a comorbid neurologic diagnosis (ND) or neurogenic bladder dysfunction after a staged neuromodulation procedure for refractory bladder symptoms. ⋯ Patients with neurogenic bladder dysfunction experience benefits after neuromodulation similar to the benefits experienced by those without coexisting neurologic conditions.
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To evaluate long-term follow-up of a phase II trial of chemohormonal therapy in 62 men with prostate cancer biochemical relapse (BR). ⋯ Chemotherapy plus ADT for BR resulted in durable (>5 years) complete responses (<0.1 ng/mL) in 7 men (11%). Twenty-four percent of men have not re-initiated ADT 5 years from completion of protocol therapy.
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To test our hypothesis that surgeon-placed paravertebral block (PVB) placement during open renal surgery is effective, feasible, and safe. Neuraxial analgesia represents the current standard of care for perioperative anesthesia for open renal surgery. However, potential catastrophic complications such as neuraxial bleeding and infection may occur. An alternative to neuraxial analgesia widely used in thoracic surgery is the surgeon-placed PVB. ⋯ PVB represents a safe and effective surgeon-placed alternative to neuraxial analgesia for open renal operative procedures.
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Randomized Controlled Trial
Fenoldopam and renal function after partial nephrectomy in a solitary kidney: a randomized, blinded trial.
To test the hypothesis that fenoldopam administration ameliorates ischemic injury, preserving the glomerular filtration rate and serum creatinine postoperatively after partial nephrectomy in patients with a solitary kidney. ⋯ Fenoldopam administration did not preserve renal function in the clinical setting of renal ischemia during solitary partial nephrectomy, as evidenced by changes in the glomerular filtration rate or serum creatinine.
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To ascertain the reliability of low-dose computed tomography (CT) compared with standard CT in the determination of stone size, density, and skin-to-stone distance (SSD). ⋯ No significant difference was found in the measurement of stone size, Hounsfield units, or SSD between the low-dose and conventional-dose CT scans. However, the low-dose CT scans resulted in a marked reduction in the radiation dose to the patient.