Burns : journal of the International Society for Burn Injuries
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Comparatively little attention has been given to the impact of smaller burns (less than 20% body surface area) on patients' health status after their return to normal life. The objective of this study was to investigate patients' own assessment of their physical and psychological health 3-4 months after discharge from in-patient treatment. A postal survey was employed which utilised: (a) personal and employment status questions; (b) a short health status questionnaire which was developed for use with this group of patients; (c) the hospital anxiety and depression scale (HAD); (d) the impact of event scale (IES). ⋯ Physical and social function were reported to be affected at the follow-up point in a minority of patients. The greatest impact of the injury was on levels of anxiety and response to trauma-related stress, as measured by the HAD and IES instruments - almost one third of the responders (15 patients) had clinically significant scores on either or both dimensions of the IES. Factors which may be associated with the response to trauma-related stress are discussed.
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Childhood burns in Egypt are a significant problem, especially in families of low socioeconomic status. These families live in overcrowded flats, which lack proper hygiene and tend to use kerosene stoves, which lack any safety measures. Three hundred and five burned children presented to the burn unit of Ain Shams University over a 20 month period. ⋯ There was an increase in the incidence between the ages of 4 to 6 years. Scalds formed 56.7% of the cause of burns, while 38.6% were due to flame. In 3 and 1.6% the cause of burn was electrical and chemical, respectively. 20 patients were victims of industrial accidents showing a major problem of entrance of children between 8-15 years of lower socioeconomic class into the labor force. 87.2% of the patients had minor burns while 13 children (4.3%) died of the consequences of burns during the period of the study.
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The concentration of orally administered sparfloxacin (SPFX), an antimicrobial agent, in exudates from the suture wounds beneath occlusive dressings has been measured. Twenty-one patients who received oral therapy with 100 mg of SPFX prior to surgery and 200 mg/day of SPFX after surgery were studied. ⋯ SPFX values were 0.801+/-0.340 microg/ml (mean+/-SD). The results suggest that wound exudates beneath the occlusive dressing have concentrations of SPFX high enough to prevent infection in most cases when administered orally.
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Lymphedema of an extremity is a rare complication of local burns, due to intact deep lymphatics. Here we present a case of delayed lymphedema of the foot, developing due to deep scarring after local burns.
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Failure of GI tract mucosa to act as a barrier against bacterial translocation (BT) has been proposed as a potential source of sepsis and subsequent multiple organ failure post thermal injury. Nitric oxide (NO) is an inorganic radical produced by NO synthase (NOS) from L-arginine. Gut mucosal constitutive NOS (cNOS) provides protection for itself. ⋯ Nitrotyrosine immunostaining of the intestinal mucosa showed a decrease in the SMT-treated group. These findings suggest that SMT, a specific inhibitor for iNOS improves the barrier function after burn by suppression of the intestinal mucosal iNOS activity. The decrease in NO production resulted in decreased formation of peroxynitrite and subsequently decreased damage of mucosal tissue.