Burns : journal of the International Society for Burn Injuries
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Advancements in resuscitative care and burn surgery have improved survival rates after extensive burn injuries, shifting focus to enhancing the quality of survival. Conventional treatment with split-thickness skin grafts (STSG) presents limitations such as donor-site morbidity, limited availability in extensive burn injuries, and hypertrophic scarring. Tissue engineering aims to address these drawbacks by developing optimal skin substitutes. This systematic review aims to provide an overview of the current applications of cultured cells in burn surgery, encompassing diverse approaches and addressing existing challenges to enhance burn wound management and improve patient outcomes. ⋯ Results are promising, though standardization of cultured skin substitutes and robust clinical trials with larger populations and appropriate comparators are still lacking.
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Demographic data reveal a correlative relationship between facial burns and profoundly impaired dental health, while inhalation injury correlates with a high Periodontal Screening and Recording Index, both of which significantly reduce quality of life for the burn injury patient. Despite these facts, few if any burn centers surveyed in the U. S. or Germany enlist specialized services and well-defined follow-up protocols for patients who might well be at risk. ⋯ Thermal injury patterns to perioral-related and dental structures is increasingly being recognized. This review delineates current burn-related dental health pathology and when available the underlying causation. These findings may help guide future research as well as therapeutic strategies to improve dental health and outcome for our patients.