Burns : journal of the International Society for Burn Injuries
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Randomized Controlled Trial
Illusory movements for immobile patients with extensive burns (IMMOBILE): A randomized, controlled, cross-over trial.
Patients who have sustained extensive burns frequently exhibit substantial damage to skeletal muscle and associated complications. The rehabilitation of these patients can be challenging due to the nature of the injury and the subsequent complications. Nevertheless, there is a possibility that functional proprioceptive stimulation (illusory movements) may facilitate effective rehabilitation in patients with limited physiotherapy options. Nevertheless, this approach has yet to be tested in patients with burn injuries. ⋯ Compared to physical therapy alone, two daily sessions of functional proprioceptive stimulation in addition to usual physical therapy in patients with extensive burns did not change energy expenditure, insulin sensitivity, nitrogen balance, or energy substrate oxidation. At cellular level, the intervention improved the capacity of aerobic phosphorylation in skeletal muscle mitochondria. Clinical effects remain to be demonstrated in adequately powered trials.
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Multicenter Study
Psychological resilience and associated factors in caring for mass burn patients among rescue nurses: A cross-sectional study.
This current study explored the relationship between challenge-hindrance stressors, coping style, and psychological resilience among rescue nurses caring for mass burn patients. ⋯ In mass burns accidents, rescuer nurses have a medium level of psychological resilience, which positively and significantly correlated with challenge stressors and positive coping style. It is suggested that more attention should be devoted to the target population to formulate effective intervention plans, reduce psychological impact, and improve their capacity for coping with disasters.
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Randomized Controlled Trial
The effects of inhalation aromatherapy on pain, anxiety, and sleep quality in burn patients: A randomized controlled study.
Patients suffering from burn injuries experience high levels of pain, anxiety, and sleep problems. These symptoms negatively affect the healing process of patients. In this study, it was aimed to determine the effect of inhalation aromatherapy applied with lavender essential oil on pain, anxiety, and sleep quality in burn patients. ⋯ It was determined that inhalation aromatherapy applied to burn patients reduced the level of pain and increased sleep quality. Aromatherapy is recommended for healthcare professionals to reduce pain and improve sleep quality in burn patients.
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Multicenter Study
Patient-reported scar quality in paediatric and adult burn patients: A long-term multicentre follow-up study.
Burn scar maturation can take several years but is generally studied shortly after injury. Therefore, we investigated patient-reported scar quality up to 5-7 years post-burn. ⋯ Two-thirds of patients with burns up to 20 % TBSA scored the quality of their scars worse at 63 months compared to 28 months post-burn. Whether this corresponds to increased dissatisfaction with scars in the long term should be further investigated. These new insights add to the body of knowledge on scar maturation and underscores the importance of discussing patients' expectations.
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Resveratrol promotes diabetic wound healing by inhibiting ferroptosis in vascular endothelial cells.
Diabetic wounds are a common complication of diabetes, with alarming disability and mortality rates. Ferroptosis plays an essential role in the occurrence and development of diabetes mellitus and its complications, suggesting that mitigating ferroptosis can be used as a potential therapeutic strategy. Resveratrol (RSV) can promote the angiogenesis of diabetic wounds, but its molecular mechanism is unclear, and RSV has a role in regulating ferroptosis. Therefore, we speculated that RSV could promote the angiogenesis of diabetic wounds and accelerate wound healing by regulating ferroptosis. ⋯ In diabetic wounds, AGEs can lead to ferroptosis in HUVECs. RSV can inhibit AGE-induced ferroptosis in HUVECs, further promoting angiogenesis in diabetic wounds, and ultimately accelerating wound healing.