European journal of gastroenterology & hepatology
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Eur J Gastroenterol Hepatol · Feb 2013
Meta AnalysisType 2 diabetes mellitus and the risk of acute pancreatitis: a meta-analysis.
Epidemiological evidences indicate that individuals with diabetes may have an increased risk of acute pancreatitis. Therefore, we carried out a meta-analysis to examine the present evidence and to identify the association between type 2 diabetes mellitus and the risk of acute pancreatitis. ⋯ These outcomes strongly support the relationship between type 2 diabetes mellitus and an increased risk of acute pancreatitis. More fundamental research should be carried out to elucidate the biological mechanisms.
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Eur J Gastroenterol Hepatol · Nov 2008
Review Meta Analysis Comparative StudyRifaximin versus nonabsorbable disaccharides in the management of hepatic encephalopathy: a meta-analysis.
To compare the positive and negative effects of rifaximin and nonabsorbable disaccharides in patients with hepatic encephalopathy. ⋯ Rifaximin is not superior to nonabsorbable disaccharides for acute or chronic hepatic encephalopathy in the long-term or short-term treatment except that it may be better tolerated. Further studies on larger populations are required to provide more sufficient evidence for assessment of the use of rifaximin.
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Eur J Gastroenterol Hepatol · Dec 2007
Review Meta Analysis Comparative StudyDo the benefits of metal stents justify the costs? A systematic review and meta-analysis of trials comparing endoscopic stents for malignant biliary obstruction.
A variety of stent designs has been studied for endoscopic stenting of the bile duct in patients with malignant biliary obstruction. Although metal stents are associated with longer patency, their costs are significantly higher than plastic stents. ⋯ Endoscopic metal stents for malignant biliary obstruction are associated with significantly higher patency rates than plastic stents as early as 4 months after insertion. Metal stents will be cost-effective if the unit cost of additional endoscopic retrograde cholangiopancreatographies per patient exceeds $1820.
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Eur J Gastroenterol Hepatol · Nov 2007
Meta AnalysisSuspected choledocholithiasis: endoscopic ultrasound or magnetic resonance cholangio-pancreatography? A systematic review.
There is a lack of consensus on the optimal noninvasive strategy for patients with suspected choledocholithiasis after a negative transabdominal ultrasound and/or computed tomography. A meta-analysis was conducted to compare the diagnostic ability of endoscopic ultrasound (EUS) and magnetic resonance cholangio-pancreatography (MRCP) in patients with suspected common bile duct (CBD) stones. ⋯ The analysis demonstrated that, with respect to sensitivity, specificity and accuracy, there was no statistically significant difference between EUS and MRCP for the detection of choledocholithiasis. Our meta-analysis of prospective comparison of MRCP and EUS for the detection of choledocholithiasis yielded statistically similar diagnostic values for both techniques.
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Eur J Gastroenterol Hepatol · Apr 2006
Review Meta AnalysisReview in depth and meta-analysis of controlled trials on colorectal cancer screening by faecal occult blood test.
Several randomized studies have shown that colorectal cancer (CRC) screening by faecal occult blood test (FOBT) reduces CRC mortality. These trials have different designs, especially concerning FOBT frequency and duration, as well as the length of follow-up after stopping FOBT campaigns. ⋯ Biennial FOBT decreased CRC mortality by 14% when performed over 10 years, without evidence-based benefit on CRC mortality when performed over a longer period. No independent predictors of CRC mortality reduction have been identified in order to allow a CRC screening programme in any subgroups of subjects at risk.