European journal of internal medicine
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Eur. J. Intern. Med. · Aug 2024
Observational StudyRelation of plasma neuropeptide-Y with myocardial function and infarct severity in acute ST-elevation myocardial infarction.
Acute myocardial infarction is associated with the release of the co-transmitter neuropeptide-Y (NPY). NPY acts as a potent vasoconstrictor and is associated with microvascular dysfunction after ST-elevation myocardial infarction (STEMI). This study comprehensively evaluated the association of plasma NPY with myocardial function and infarct severity, visualized by cardiac magnetic resonance (CMR) imaging, in STEMI patients revascularized by primary percutaneous coronary intervention (PCI). ⋯ High plasma levels of NPY, measured 24h after STEMI, were independently associated with lower LVEF, decreased GLS, larger IS as well as presence of MVO, indicating plasma NPY as a novel clinical risk marker post STEMI.
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Eur. J. Intern. Med. · Aug 2024
Observational StudyPrognostic value of 18 FDG-PET at diagnosis and follow-up in giant cell arteritis: An observational restrospective study.
To evaluate the ability of 18FDG PET/CT, at diagnosis of giant cell arteritis (GCA) and during follow-up, to predict occurrence of relapse in large-vessel GCA (LV-GCA). ⋯ PET vascular activity scores at diagnosis and at follow-up PET/CT performed outside a period of GCA activity do not display high performance to predict the occurrence of subsequent relapse in LV-GCA patients.
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Eur. J. Intern. Med. · Aug 2024
Letter Case ReportsInfective endocarditis complicated with heart failure.