European journal of internal medicine
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Eur. J. Intern. Med. · Aug 2019
Multicenter StudyExternal validation of the CACE-HF risk score for mortality in patients with heart failure.
To validate externally the CACE-HF clinical prediction rule, which predicts 1-year mortality in patients with heart failure (HF). ⋯ The results of the external validation of the CACE-HF risk score show that although the capacity for discrimination was slightly lower than in the derivation cohort, the calibration was excellent. This tool, therefore, can assist in decision-making in the management of these patients.
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Eur. J. Intern. Med. · Aug 2019
Multicenter Study Observational StudyVedolizumab is effective and safe in real-life treatment of inflammatory bowel diseases outpatients: A multicenter, observational study in primary inflammatory bowel disease centers.
Italian data currently available in managing ulcerative colitis (UC) and Crohn's disease (CD) patients with vedolizumab (VDZ) are coming just from secondary and tertiary centers. The present study aimed to assess the real-life efficacy and safety of VDZ to achieve remission in inflammatory bowel diseases (IBD) outpatients in primary gastroenterology centers. ⋯ VDZ is effective and safe in IBD outpatients, especially in UC patients.
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Eur. J. Intern. Med. · Jul 2019
Multicenter Study Comparative StudyDelirium in patients with dementia and in children: Overlap of symptoms profile and possible role for future diagnosis.
Delirium in the extremes of the age spectrum may show similarities in presentations, and these similarities may provide information to develop tools for the diagnosis of delirium superimposed on dementia (DSD). We sought to investigate the symptom profile and subtypes of delirium in patients with dementia, and in infants and preschool children. ⋯ The study reports similarities in the symptoms profile of delirium in a cohort of patients with dementia and delirium, and in infants and preschool-aged children with delirium. These preliminary findings might be informative to design future studies adapting delirium assessments used in in infants and preschool-aged children to patients with dementia, especially in the moderate to severe stages.
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Eur. J. Intern. Med. · Jul 2019
Multicenter Study Observational StudyEffect of risk of malnutrition on 30-day mortality among older patients with acute heart failure in Emergency Departments.
Little is known about the prevalence and impact of risk of malnutrition on short-term mortality among seniors presenting with acute heart failure (AHF) in emergency setting. The objective was to determine the impact of risk of malnutrition on 30-day mortality risk among older patients who attended in Emergency Departments (EDs) for AHF. ⋯ The risk of malnutrition assessed by the MNA-SF is associated with 30-day mortality in older patients with AHF who were attended in EDs. Routine screening of risk of malnutrition may help emergency physicians in decision-making and establishing a care plan.
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Eur. J. Intern. Med. · Jun 2019
Multicenter StudyPredictive value of serum myostatin for the severity and clinical outcome of heart failure.
The exact relationship between serum myostatin and the severity and prognosis of chronic heart failure (CHF) is unclear. In this study, we investigated the association between serum myostatin and the severity and prognosis in patients with CHF. ⋯ Serum myostatin levels can reflect the severity of CHF and be a predictor of adverse prognosis in CHF patients.