European journal of internal medicine
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Eur. J. Intern. Med. · Jan 2025
Multicenter StudyThe impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study).
The COVID-19 pandemic had a major impact on medical care. This study evaluated the influence of the pandemic on blood pressure (BP) control and hypertension phenotypes as assessed by office and 24-hour ambulatory BP monitoring (ABPM). ⋯ These results indicate a negative impact of the COVID-19 pandemic on BP control assessed by hypertension phenotypes.
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Homocysteine (Hcy) levels are elevated in different conditions, including cardiovascular diseases (CVD), diabetes, and metabolic-associated steatotic liver disease (MASLD). In this observational retrospective study, we analyzed Hcy levels in a population of 901 outpatients, considering its putative etiological role in MASLD. ⋯ Our data suggest an intriguing scenario whereby HHcy is present in patients with MASLD and is associated to lower vitamin D and altered glucose and lipid profile. Thus, considering Hcy levels may help clinicians with the management of patients with increased MASLD risk.
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Eur. J. Intern. Med. · Jan 2025
TLR4 and TNF-α single nucleotide polymorphisms in patients with brucellosis: Association with infection complications.
To investigate associations of the carriage of single nucleotide polymorphisms (SNPs) of proteins involved in the immune response of patients with brucellosis. ⋯ In our cohort, the association of one TNF SNP of patients with brucellosis, in particular spondylodiscitis, might be prognostic whereas further investigation of the exact role in the host immune response is required.