European journal of internal medicine
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Herein we recount the legacy of Sir David Roxbee Cox (15 July 1924 - 18 January 2022) from the perspective of practicing clinicians. His-pioneering work in developing the logistic and Cox proportional hazard regression models revolutionized the analysis and interpretation of categorical and time-to-event survival outcomes in modern medicine. This legacy is an inspiration for all those who follow on Sir David Cox's path.
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Eur. J. Intern. Med. · Feb 2022
EditorialPulmonary embolism - An EFIM guideline critical appraisal and adaptation for practicing clinicians.
Several trials have been conducted in the last decades that challenged the management of patients with acute pulmonary embolism (PE) in terms of diagnosis and treatment. Updated international clinical practice guidelines (CPGs) endorsed the evidence from these trials. The aim of this document was to adapt recommendations from existing CPGs to assist physicians in decision making concerning specific and complex scenarios related to acute PE. ⋯ By the use of proper methodology for the adaptation process, this document offers a simple and updated guide for practicing clinicians dealing with complex patients.