The British journal of general practice : the journal of the Royal College of General Practitioners
-
Long-term antidepressant use, much longer than recommended by guidelines, may cause harmful effects and generate unnecessary costs. ⋯ Deprescribing long-term AD is a difficult and complex process for HPs. The review found evidence that the barriers far outweigh the facilitators. More education on the lack of evidence for the long-term effect of AD and the risks of long-term use, guidance on managing long-term use, and support for HPs and patients is needed to increase long-term AD discontinuation. Further research from an HP perspective other than GPs is required and should also explore how HPs can be supported in managing discontinuation ADs.