The British journal of general practice : the journal of the Royal College of General Practitioners
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Randomized Controlled Trial
GPs' willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a factorial randomised trial investigating factors influencing decisions.
The National Institute for Health and Care Excellence (NICE) 2020 guidelines recommends aspirin for colorectal cancer prevention for people with Lynch syndrome. Strategies to change practice should be informed by understanding the factors influencing prescribing. ⋯ It is unlikely that providing information on clinical guidance, trial results, and information comparing benefits and harms will increase aspirin prescribing for Lynch syndrome in primary care. Alternative multilevel strategies to support informed prescribing may be warranted.
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Randomized Controlled Trial Observational Study
Antibiotic effectiveness for children with lower respiratory infections: prospective cohort and trial in primary care.
Antibiotics are commonly prescribed for children with chest infections but there is little randomised evidence and trials commonly recruit selected populations, which undermines their applicability. ⋯ Antibiotics for uncomplicated chest infections, even in a sample of more unwell children, are unlikely to be clinically very effective.
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Randomized Controlled Trial
Comparing GPs' antibiotic prescribing decisions to a clinical prediction rule: an online vignette study.
The 'STARWAVe' clinical prediction rule (CPR) uses seven factors to guide risk assessment and antibiotic prescribing in children with cough (Short illness duration, Temperature, Age, Recession, Wheeze, Asthma, Vomiting). ⋯ GPs use some, but not all, STARWAVe factors when making unaided risk assessments and prescribing decisions. Such discrepancies must be considered when introducing CPRs to clinical practice.
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Randomized Controlled Trial
Patient experiences of GP-led colon cancer survivorship care: a Dutch mixed-methods evaluation.
Colon cancer survivorship care constitutes both follow-up and aftercare. GP involvement may help to personalise care. ⋯ Patients experienced a high quality of colon cancer survivorship care from both GPs and surgeons. If the GP is going to be more involved, patients require a clear understanding of roles and responsibilities.
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Randomized Controlled Trial
Advance care planning in primary care for patients with gastrointestinal cancer: feasibility randomised trial.
Advance (anticipatory) care planning (ACP) requires discussions between patients and healthcare professionals about planning for future deterioration in health. ACP improves care coordination but uptake is limited and often deferred. ⋯ An RCT of ACP for people with incurable cancer in primary care is feasible. Patient, carer, and GP attitudes and behaviours determined acceptability and timing of care planning.