The British journal of general practice : the journal of the Royal College of General Practitioners
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Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial
Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial.
Acute gastroenteritis (AGE) affects almost all children aged ≤5 years. In secondary care, ondansetron was found to be effective at reducing vomiting. ⋯ Children with AGE and increased risk of dehydration due to vomiting could be treated with ondansetron in primary care to stop vomiting more quickly and increase parental satisfaction with treatment. These results could be used to improve the quality and efficacy of general practice medicine.
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Randomized Controlled Trial
Increasing uptake of NHS Health Checks: an RCT using GP computer prompts.
Public Health England wants to increase the uptake of the NHS Health Check (NHSHC), a cardiovascular disease prevention programme. Most invitations are sent by letter, but opportunistic invitations may be issued and verbal invitations have a higher rate of uptake. Prompting staff to issue opportunistic invitations might increase uptake. ⋯ Prompts on computer systems in general practice were effective at improving the uptake of the NHSHC, especially for males and younger patients.
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Randomized Controlled Trial
Nortriptyline for pain in knee osteoarthritis in general practice: a double blind randomised controlled trial.
Osteoarthritis (OA) of the knee is a common cause of chronic pain. Analgesics that are currently available have limited efficacy and may be poorly tolerated. Tricyclic antidepressants are used as analgesics for other chronic conditions, but they have not been evaluated as analgesics in OA. ⋯ This study suggests nortriptyline does not significantly reduce pain in people with knee OA. The adverse effect profile was as expected.
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Randomized Controlled Trial
Smoking cessation intervention in Australian general practice: a secondary analysis of a cluster randomised controlled trial.
GPs have limited capacity to routinely provide smoking cessation support. New strategies are needed to reach all smokers within this setting. ⋯ A pharmacist-coordinated interdisciplinary smoking cessation intervention when integrated in a general practice setting had no advantages over usual care. Further research is needed to evaluate the effect of HMR and home-based pulmonary rehabilitation on smoking abstinence in smokers with COPD.
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Randomized Controlled Trial
Targeted encouragement of GP consultations for possible cancer symptoms: a randomised controlled trial.
For some common cancers, survival is lower in the UK than in comparable high-income countries. ⋯ Targeted interventions of this nature can change behaviour; there is a need to develop interventions that can be more effective at engaging patients with primary care. This study demonstrates that targeted interventions promoting both awareness of possible cancer symptoms and earlier health seeking, can change behaviour. There is a need to develop and test interventions that can be more effective at engaging the most at-risk patients.