Cerebrovascular diseases
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Cerebrovascular diseases · Jan 2009
ReviewQuality of life after stroke: the importance of a good recovery.
Health-related quality of life (HRQoL) is a recognized and important outcome after stroke. An increased survival and the presence of moderate impairment in long-term stroke survivors impact their HRQoL. ⋯ Physical and psychosocial well-being is greatly affected in stroke survivors and their caregivers.
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Cerebrovascular diseases · Jan 2009
Recovery after ischemic stroke: criteria for good outcome by level of disability at day 7.
Ischemic stroke is a leading cause of morbidity. Assessing the chances of recovery is critical to optimize poststroke care. ⋯ We identified clinical variables that predict good outcome, are specific to each day 7 mRS tier, and enable easy and informative assessment of the patient's likelihood of achieving varying degrees of recovery at day 90. These results may be useful in both clinical practice and research but require validation in an independent patient cohort.
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Cerebrovascular diseases · Jan 2009
Normal magnetic resonance perfusion-weighted imaging in lacunar infarcts predicts a low risk of early deterioration.
Current clinical tools to identify lacunar infarct patients at risk of deterioration are inadequate, and imaging techniques to predict fluctuation and deterioration would be of value. We sought to determine the occurrence of MRI perfusion-weighted imaging (PWI) abnormalities in lacunes, and whether they help predict clinical and radiological outcome. ⋯ MR-PWI abnormalities are seen in two thirds of lacunar infarcts, and are associated with stroke rather than TIA. Normal PWI identifies patients at low risk of early clinical deterioration.
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Cerebrovascular diseases · Jan 2009
Hyperdense middle cerebral artery sign on admission CT scan--prognostic significance for ischaemic stroke patients treated with intravenous thrombolysis in the safe implementation of thrombolysis in Stroke International Stroke Thrombolysis Register.
Hyperdense middle cerebral artery sign (HMCAS) on CT scan before stroke thrombolysis is associated with increased risk for haemorrhage and unfavourable outcome in several small studies. ⋯ HMCAS patients had severer stroke and a worse 3-month outcome. The risk for SICH per the SITS-MOST definition was similar compared to non-HMCAS patients, although increased per the RCT definition. There is not sufficient evidence to exclude these patients from intravenous thrombolysis. Combined treatment approaches might be considered in the perspective of the severe outcome and evaluated in RCTs.
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Cerebrovascular diseases · Jan 2009
Five-year survival after first-ever ischaemic stroke is worse in total anterior circulation infarcts: the SINPAC cohort.
Few studies have addressed predictors of long-term mortality after first-ever ischaemic stroke. ⋯ Our study extends the prognostic value of the OCSP classification to 5-year survival.