Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
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Randomized Controlled Trial Comparative Study
Prospective, randomized, double-blind, placebo-controlled trial of ulinastatin for prevention of hyperenzymemia after double balloon endoscopy via the antegrade approach.
Double balloon endoscopy (DBE) allows the entire small intestine to be viewed using a combination of antegrade and retrograde approaches. Acute pancreatitis is a serious complication of antegrade DBE with no effective prophylactic treatment currently available. Ulinastatin has been shown to be effective for the prevention of pancreatitis following endoscopic retrograde cholangiopancreatography. We therefore assessed the efficacy of ulinastatin for hyperenzymemia after antegrade DBE. ⋯ The results of this trial suggest that ulinastatin does not prevent hyperenzymemia following antegrade DBE.
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Randomized Controlled Trial
Administration of additional analgesics can decrease the incidence of paradoxical reactions in patients under benzodiazepine-induced sedation during endoscopic transpapillary procedures: prospective randomized controlled trial.
The aim of the present study was to evaluate the efficacy and safety of giving pentazocine as an analgesic with benzodiazepine during endoscopic retrograde cholangiopancreatography (ERCP). ⋯ The administration of pentazocine is significantly reduced the incidence of PR's in patients under midazolam induced sedation during ERCP.
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Letter Randomized Controlled Trial
Is topical pharyngeal anesthesia necessary in esophagogastroduodenoscopy in all unsedated patients?
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Randomized Controlled Trial Comparative Study
Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer.
Although the treatment of early gastric cancer with endoscopic submucosal dissection (ESD) has been widely carried out, a standardized method of sedation for ESD has not been established. The purpose of the present study was to evaluate the efficacy and safety of sedation with dexmedetomidine (DEX). ⋯ Sedation with DEX is effective and safe for patients with gastric tumors who are undergoing ESD.