Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Jul 2010
Reproducibility of in vivo magnetic resonance imaging-based measurement of myelin water.
To evaluate the reproducibility of multicomponent quantitative T(2) (QT2) measurements, in particular the myelin water fraction (MWF), to determine the sensitivity of this method for monitoring myelin changes in longitudinal studies and to provide a basis for correctly powering such studies. ⋯ The reproducibility of QT2 measurements using existing methods is moderate and the method can be used in longitudinal studies, with careful consideration of the methodologic variability and an appropriate group size.
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J Magn Reson Imaging · Jul 2010
Visualization of cerebral microbleeds with dual-echo T2*-weighted magnetic resonance imaging at 7.0 T.
To assess the visualization of cerebral microbleeds with dual echo T2*-weighted imaging at 7.0 T magnetic resonance imaging (MRI). ⋯ T2*-weighted imaging at two echo times at 7.0 T combines the advantages of the first and second echo. Microbleeds visible on the first echo show large contrast with the surrounding tissue, even in the presence of paramagnetic ferritin. The second echo enables visualization of smaller microbleeds than the first echo.
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J Magn Reson Imaging · Jul 2010
Utility of diffusion-weighted MRI in distinguishing benign and malignant hepatic lesions.
To evaluate apparent diffusion coefficient (ADC) values for characterization of a variety of focal liver lesions and specifically for differentiation of solid benign lesions (focal nodular hyperplasia [FNH] and adenomas) from solid malignant neoplasms (metastases and hepatocellular carcinoma [HCC]) in a large case series. ⋯ Benign lesions have higher mean ADC values than malignant lesions. However, ADC values of solid benign lesions (FNH and adenomas) are similar to malignant lesions (metastases, HCC) limiting the value of diffusion weighted imaging (DWI) for differentiating solid liver masses.