Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Oct 2018
Quantitative susceptibility mapping (QSM) minimizes interference from cellular pathology in R2* estimation of liver iron concentration.
A challenge for R2 and R2* methods in measuring liver iron concentration (LIC) is that fibrosis, fat, and other hepatic cellular pathology contribute to R2 and R2* and interfere with LIC estimation. ⋯ 1 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;48:1069-1079.
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J Magn Reson Imaging · Oct 2018
Radiomics Strategy for Molecular Subtype Stratification of Lower-Grade Glioma: Detecting IDH and TP53 Mutations Based on Multimodal MRI.
Noninvasive detection of isocitrate dehydrogenase (IDH) and TP53 mutations are meaningful for molecular stratification of lower-grade gliomas (LrGG). ⋯ 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;48:916-926.
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J Magn Reson Imaging · Oct 2018
Variable impact of CSF flow suppression on quantitative 3.0T intracranial vessel wall measurements.
Flow suppression techniques have been developed for intracranial (IC) vessel wall imaging (VWI) and optimized using simulations; however, simulation results may not translate in vivo. ⋯ 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;48:1120-1128.
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Renal function varies according to the nature and stage of diseases. Renal functional magnetic resonance imaging (fMRI), a technique considered superior to the most common method used to estimate the glomerular filtration rate, allows for noninvasive, accurate measurements of renal structures and functions in both animals and humans. ⋯ Function-related imaging markers can be acquired via renal fMRI, encompassing water molecular diffusion, perfusion, and oxygenation. This review focuses on the progression and challenges of the main renal fMRI methods, including dynamic contrast-enhanced MRI, blood oxygen level-dependent MRI, diffusion-weighted imaging, diffusion tensor imaging, arterial spin labeling, fat fraction imaging, and their recent clinical applications.
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J Magn Reson Imaging · Oct 2018
Tissue characterization of uterine fibroids with an intravoxel incoherent motion model: The need for T2 correction.
Diminished signal intensity of uterine fibroids in T2 -weighted images is routinely used as a qualitative marker of fibroid hypoperfusion. However, quantitative classification of fibroid perfusion with intravoxel incoherent motion (IVIM) model-based metrics is not yet clinically accepted. ⋯ 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;48:994-1001.