Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Feb 2019
Convolutional Neural Network Using a Breast MRI Tumor Dataset Can Predict Oncotype Dx Recurrence Score.
Oncotype Dx is a validated genetic analysis that provides a recurrence score (RS) to quantitatively predict outcomes in patients who meet the criteria of estrogen receptor positive / human epidermal growth factor receptor-2 negative (ER+/HER2-)/node negative invasive breast carcinoma. Although effective, the test is invasive and expensive, which has motivated this investigation to determine the potential role of radiomics. ⋯ 4 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:518-524.
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J Magn Reson Imaging · Feb 2019
Disrupted functional connectivity and activity in the white matter of the sensorimotor system in patients with pontine strokes.
White matter (WM) blood oxygenation level-dependent (BOLD) signals are reported to be related to neural activity. However, sensitivity of WM BOLD signals to disease remains unclear. ⋯ 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:478-486.
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J Magn Reson Imaging · Feb 2019
3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects.
Semiquantitative assessment of MRI plays a central role in musculoskeletal research; however, in the clinical setting MRI reports often tend to be subjective and qualitative. Grading schemes utilized in research are not used because they are extraordinarily time-consuming and unfeasible in clinical practice. ⋯ 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:400-410.
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J Magn Reson Imaging · Feb 2019
Interreader agreement of PI-RADS v. 2 in assessing prostate cancer with multiparametric MRI: A study using whole-mount histology as the standard of reference.
Most studies assessing interreader agreement of Prostate Imaging Reporting and Data System v. 2 (PI-RADS v2) have used biopsy as the standard of reference, thus carrying the risk of not definitively noting all existent cancers. ⋯ 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:546-555.
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J Magn Reson Imaging · Feb 2019
Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis.
Multiple sclerosis (MS) is a chronic disease affecting the human central nervous system (CNS) and leading to neurologic disability. Although conventional MRI techniques can readily detect focal white matter (WM) lesions, it remains challenging to quantify tissue damage in normal-appearing gray matter (GM) and WM. ⋯ 2 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2019;49:487-498.