Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Oct 2005
3D volume-selective turbo spin echo for carotid artery wall imaging with navigator detection of swallowing.
To improve 3D volume-selective turbo spin echo (TSE) carotid artery wall imaging by incorporating navigators to reduce artifacts caused by swallowing. ⋯ The clarity of vessel wall delineation and the apparent efficiency of blood suppression are reduced by swallowing during acquisition. Both motion blurring and quality of blood suppression are factors that can be improved with the use of a navigator accept/reject method.
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J Magn Reson Imaging · Oct 2005
Heterogeneity in the angiogenic response of a BT474 human breast cancer to a novel vascular endothelial growth factor-receptor tyrosine kinase inhibitor: assessment by voxel analysis of dynamic contrast-enhanced MRI.
To investigate the heterogeneity in the angiogenic response of a human breast cancer xenograft to a novel vascular endothelial growth factor (VEGF)-receptor tyrosine kinase inhibitor, AG-013736, using dynamic contrast-enhanced MR imaging (DCE-MRI). ⋯ This study demonstrates the value of histogram analysis of maps of pharmacokinetic parameters for assessing heterogeneity in tumor response to antiangiogenic therapy. Changes in the number of voxels within certain segments of the Kps histogram were the most sensitive variable for separating control from AG-treated tumors.
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J Magn Reson Imaging · Sep 2005
The impact of partial-volume effects in dynamic susceptibility contrast magnetic resonance perfusion imaging.
To demonstrate the degree of the cerebral blood flow (CBF) estimation bias that could arise from distortion of the arterial input function (AIF) as a result of partial-volume effects (PVEs) in dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI). ⋯ PVE can induce significant CBF estimation biases. In addition, the MTT dependence of CBF accuracy raises doubts of the validity of adopting a single cross-calibration factor (i.e., setting normal white matter to 22 mL minute(-1) (100 g)(-1)) to obtain CBF values with absolute units. The impact of PVE may be reduced by decreasing the maximum arterial signal drop in the perfusion images. To correct the AIF distortions introduced by PVE, the nonlinear relationship between the impact of PVE on MR signal intensity and contrast concentration function must be considered.
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J Magn Reson Imaging · Sep 2005
Combined T1-T2 mapping of human femoro-tibial cartilage with turbo-mixed imaging at 1.5T.
To evaluate the influence of Gd-DTPA on cartilage T2 mapping using turbo-mixed (tMIX) imaging, and to show the possible usefulness of the tMIX technique for simultaneously acquiring T1 and T2 information in cartilage. ⋯ The absolute difference of pre- and postcontrast T2 is very small and is ruled out using the back-calculation algorithm. Combined T1-T2 tMIX cartilage mapping is a valuable alternative for separate T1 and T2 cartilage mapping.
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J Magn Reson Imaging · Sep 2005
Comparative StudyComparison of Gd [DTPA-bis (2-aminoethoxy) ethane] polymeric contrast agent with gadodiamide injection for interstitial MR lymphography: experimental study with rabbits.
To compare the differences between macromolecular and small molecular contrast agents in interstitial magnetic resonance (MR) lymphography. ⋯ Interstitial MR lymphography with polymeric Gd-poly-DTPA-EOEA enhancer enables more sufficient and reliable visualization of lymph nodes compared to small molecular gadodiamide.