Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Mar 2018
Meta AnalysisPerformance of MRI for suspected appendicitis in pediatric patients and negative appendectomy rate: A systematic review and meta-analysis.
To evaluate in pediatric patients the diagnostic performance of magnetic resonance imaging (MRI) for suspected appendicitis and its negative appendectomy rate. ⋯ 3 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2018;47:767-778.
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J Magn Reson Imaging · Oct 2017
ReviewClinical quantitative susceptibility mapping (QSM): Biometal imaging and its emerging roles in patient care.
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI) of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense blooming artifacts to precise quantitative measurement of spatial biodistributions. QSM technology may be regarded to be sufficiently developed and validated to warrant wide dissemination for clinical applications of imaging isotropic susceptibility, which is dominated by metals in tissue, including iron and calcium. These biometals are highly regulated as vital participants in normal cellular biochemistry, and their dysregulations are manifested in a variety of pathologic processes. ⋯ In brief, QSM can be generated with postprocessing whenever gradient echo MRI is performed. QSM can be useful for diseases that involve neurodegeneration, inflammation, hemorrhage, abnormal oxygen consumption, substantial alterations in highly paramagnetic cellular iron, bone mineralization, or pathologic calcification; and for all disorders in which MRI diagnosis or surveillance requires contrast agent injection. Clinicians may consider integrating QSM into their routine imaging practices by including gradient echo sequences in all relevant MRI protocols.
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J Magn Reson Imaging · May 2017
ReviewLiver fibrosis: Review of current imaging and MRI quantification techniques.
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis and cirrhosis. The severity of liver fibrosis influences the decision to treat or the need to monitor hepatic or extrahepatic complications. ⋯ Further, some techniques are only available on MRI-such as spin-lattice relaxation time in the rotating frame (T1 ρ), diffusion of water molecules, and hepatocellular function based on the uptake of a liver-specific contrast agent-remain investigational in the setting of liver fibrosis staging. In this review, we summarize the key concepts, advantages and limitations, and diagnostic performance of each technique. The use of multiparametric MRI techniques offers the potential for comprehensive assessment of chronic liver disease severity.
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J Magn Reson Imaging · Mar 2017
Review3D printing from MRI Data: Harnessing strengths and minimizing weaknesses.
3D printing facilitates the creation of accurate physical models of patient-specific anatomy from medical imaging datasets. While the majority of models to date are created from computed tomography (CT) data, there is increasing interest in creating models from other datasets, such as ultrasound and magnetic resonance imaging (MRI). ⋯ Here we review the basics of 3D printing, explore the current strengths and weaknesses of printing from MRI data as they pertain to model accuracy, and discuss considerations in the design of MRI sequences for 3D printing. Finally, we explore the future of 3D printing and MRI, including creative applications and new materials.
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J Magn Reson Imaging · Jan 2017
ReviewWhole-body PET/MRI for colorectal cancer staging: Is it the way forward?
Magnetic resonance imaging (MRI) is presently the modality of choice for the local staging of rectal cancer, with positron emission tomography (PET) being optional for the evaluation of colorectal cancer. Indeed, previous studies have demonstrated that liver MRI using hepatocyte-specific contrast agents can provide high diagnostic performance in the detection of colorectal cancer liver metastases. ⋯ This review offers a brief overview of the technical considerations of the PET/MRI system, and the current status of imaging modalities in the staging of colorectal cancer. The potential of whole-body PET/MRI to improve the performance of colorectal cancer staging and the results of several recent studies will be discussed, and workflow considerations of whole-body PET/MRI for patients with colorectal cancer will be addressed.