Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Anasthesiol Intensivmed Notfallmed Schmerzther · Jun 2016
Randomized Controlled Trial[Not Available].
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Anasthesiol Intensivmed Notfallmed Schmerzther · Feb 2016
Randomized Controlled Trial[In Process Citation].
Multiresistant bacteria play an increasingly important role in everyday clinical practice. This is particularly the case in intensive care units and wards with critically ill patients. Often there is insufficient knowledge concerning diagnostic screening indications and strategies to avoid cross-transmission via infection control strategies. Hereby, we provide an orienting overview and assessment about current guidelines and recommendations with special focus on methicillin-resistant Staphylococcus aureus (MRSA) and multiresistantgramnegative bacteria (MRGN).
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Anasthesiol Intensivmed Notfallmed Schmerzther · Mar 2006
Randomized Controlled Trial Comparative Study[Comparison of a propofol-based anesthesia regimen using optimated-target-controlled-infusion (OTCI) and manually-controlled infusion (MCI) technique].
Propofol anesthesia based on target-controlled-infusion (TCI) has been shown to be superior to a manually-controlled-infusion (MCI) technique. A new optimal-target-controlled-infusion (OTCI) technique enables an individual plasma-targeted adjustment by including the concentration in the effect-compartment. This study compared practicability and costs of the new system with a conventional MCI-based propofol anesthesia regimen. ⋯ The new OTCI-system is a safe and easily controllable technique. The obvious advantage of this infusion system appears to be a reduction in propofol consumption and direct drug costs for anaesthesia lasting longer than 60 min.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Feb 2006
Randomized Controlled Trial Comparative Study[Evaluation of CVC-set].
Frequently central venous catheter sets do not contain all necessary materials. To evaluate, if combined measures using a specially arranged central venous catheter (CVC) set result in economical and clinical advantages, we compared both cost and time differences of a CVC complete set with ECG guide wire lead and an adhesive fixation with a standard set requiring additional materials, ECG fluid column lead and surgical suture. Furthermore, quality of different ECG leads, the reliability and tolerability of the adhesive fixation was compared. ⋯ The test CVC complete set allows a significant time saving and cost reduction in performing a central venous catheter line because of completely included disposable materials. CVC position control via guide wire needs less time and shows significantly better quality of ECG compared to fluid column ECG lead. An adhesive revealed to be a reliable CVC fixation comparable to a surgical suture.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Feb 2006
Randomized Controlled Trial[No potentiation of fentanyl by use of transdermal buprenorphine in patients undergoing fast-track anesthesia for open-heart surgery].
Simultaneous use of opioids with a different pharmacological profile may lead to unexpected prolongation of effects. In an open label study possible overhang in post-operative respiratory effects and vigilance was determined in a group of patients (n = 22) carrying a transdermal buprenorphine patch for at least 2 months for treatment of chronic pain, undergoing a fentanyl-based fast-track enflurane anesthetic technique for open-heart operation. Data was compared with another randomised group (n = 21) undergoing similar open-heart procedures with no other opioid than fentanyl on board. ⋯ Patients using a buprenorphine patch for the relief of chronic pain cannot be regarded as opioid naïve. Due to adaptive mechanisms and the development of tolerance, there is no prolongation of the respiratory depression induced by intraoperative fentanyl. Long-term use of transdermal buprenorphine does not lead to potentiation or prolongation of opioid effects in cardiac surgery patients.