Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Anasthesiol Intensivmed Notfallmed Schmerzther · Nov 1993
Comparative Study[High purity ryanodine for in vitro diagnosis of malignant hyperthermia].
The identification of disposition for malignant hyperthermia (MH) is performed by the halothane-caffeine contracture test in skeletal muscle. However, testing currently renders about 14% of the patients MH equivocal (MHE). To reduce this number the "ryanodine contracture test" has been proposed in addition to the established procedure. As all ryanodine preparations used until now are combinations of ryanodine and dehydroryanodine, we investigate in this study the effects of the now available high-purity ryanodine (HPR) in concentrations of 2,5 and 10 mumol/l. ⋯ The ryanodine contracture test should be added to the current diagnostics of malignant hyperthermia.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Oct 1993
[First aid and prognosis following drowning accidents. Results of a retrospective study of 115 cases].
In 115 cases of submersion the initial findings of the rescue team, the patients status in the emergency room and the course of clinical treatment were analyzed retrospectively. ⋯ Thus, there are no useful parameters that would accurately predict the individual course of a submersion victim.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Oct 1993
Comparative Study[Monitoring neuromuscular function: capnography versus relaxometry].
A notch ("curare cleft") in the plateau phase of the capnogram of the ventilated patient has been presumed to be a typical early sign of the fading effect of muscle relaxants on the diaphragm. For that reason a prospective study was done to investigate whether capnography can be used diagnostically to indicate the fading effect of vecuronium confirmed by peripheral relaxometry. ⋯ Capnography is therefore not a reliable method to indicate the fading effect of muscle relaxants.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Oct 1993
Review[The present status of blood filtration--fundamentals and the clinical significance of leukocyte depletion and microaggregate filters in blood transfusion].
In this review the role of the latest generation of leukodepletion blood filters and the adverse reaction of leukocytes i.e. alloimmunisation, immunosuppression, nonhaemolytic febrile transfusion reaction, platelet refractoriness, transmission of infectious agents are described and discussed. Leukocyte-poor blood component is indicated for patients with a history of nonhaemolytic febrile transfusion reaction, in avoiding alloimmunisation in patients waiting for transplantation or platelet refractoriness and in preventing CMV-infection. ⋯ The need of microfiltration of autologous blood is discussed. It appears that the use of 40 microns microfilters is warranted in a broad array of intensive care settings.