Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2013
Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat.
Acute kidney injury (AKI) and ischemic stroke may occur in the same cardiac surgical patient. It is not known if an interaction exists between these organ injuries. Isolated renal ischemia/reperfusion is associated with dysfunction in remote, otherwise normal organs, including the brain. In a rat model of simultaneous bilateral renal artery occlusion (BRAO) and middle cerebral artery occlusion (MCAO), the authors tested the hypothesis that AKI would worsen experimental stroke outcome. ⋯ In contrast to the effects reported for AKI on normal remote organs, AKI had no influence on infarct size or neurologic function after experimental ischemic cerebral stroke.
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J. Cardiothorac. Vasc. Anesth. · Feb 2013
Sevoflurane requirement to maintain bispectral index-guided steady-state level of anesthesia during the rewarming phase of cardiopulmonary bypass with moderate hypothermia.
The authors aimed to quantify any increase and the extent of the increase in sevoflurane requirements for maintaining hypnosis during hypothermic cardiopulmonary bypass (CPB) with the bispectral index (BIS) maintained between 40 and 50. ⋯ The sevoflurane requirement increases during the rewarming phase of hypothermic CPB. The percent increase in the requirement for sevoflurane is uniform and follows a particular pattern, which may be predicted.
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J. Cardiothorac. Vasc. Anesth. · Feb 2013
Changes in transfusion practice over time in adult patients undergoing liver transplantation.
The aim of this study was to investigate changes in transfusion practice over time in liver transplantation surgery and to evaluate potential causes for changes in practice and report associated perioperative morbidity and mortality. ⋯ When compared with patients in the early group, recent cohort patients received significantly fewer blood transfusions. The authors attribute this observation to changes in surgical technique rather than a significant alteration in transfusion triggers over the studied time period.