Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Dec 2018
Review Meta AnalysisNitric Oxide in Cardiac Surgery: A Meta-Analysis of Randomized Controlled Trials.
To investigate the efficacy and safety of perioperative administration of nitric oxide in cardiac surgery. ⋯ Perioperative delivery of inhaled nitric oxide resulted to be of no or minimal benefit in patients with pulmonary hypertension undergoing cardiac surgery. Large, randomized trials are needed to further assess its effect on major clinical outcomes and its cost-effectiveness.