Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2018
Randomized Controlled TrialMetamizole and Platelet Inhibition by Aspirin Following On-Pump Coronary Artery Bypass Grafting.
The purpose of the study was to evaluate the impact of intravenous metamizole on platelet inhibition by aspirin in patients with coronary artery disease early after on-pump coronary artery bypass grafting (CABG). ⋯ Intravenous metamizole preceded by a loading dose of aspirin did not modify platelet response to aspirin in the postoperative period after CABG.
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J. Cardiothorac. Vasc. Anesth. · Feb 2018
Observational StudyEffectiveness and Safety of Aprotinin Use in Thoracic Aortic Surgery.
To determine the effectiveness and safety of aprotinin use in adult patients undergoing thoracic aortic surgery. ⋯ The use of aprotinin demonstrated a limited effect in reducing postoperative bleeding and prevention of major bleeding events. Aprotinin did not adversely affect early outcomes and long-term survival.
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J. Cardiothorac. Vasc. Anesth. · Feb 2018
ReviewHypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction: Expecting the Unexpected.
Hypertrophic cardiomyopathy is an increasingly recognized clinical disease that carries perioperative risk. Patients may or may not carry a preoperative diagnosis, but provocable left ventricular outflow tract gradients place them at risk for hemodynamic compromise under surgical conditions. ⋯ This review focuses on the diagnostic criteria, risk factors, and management strategies for the perioperative hypertrophic cardiomyopathy patient. Finally, novel diagnostic modalities are discussed.