Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Aug 2019
Propofol-Induced Vasodilation in Human Internal Mammary Artery: Role of Potassium Channels.
The aim of this study was to investigate the vascular effects and mechanisms of propofol in the human internal mammary artery (IMA). ⋯ This study clearly reveals that propofol relaxes the IMA, and propofol-induced vasodilation may be related to large conductance calcium ion-activated potassium ion channel activation. Propofol use in coronary artery bypass surgery can be valuable via its favorable vasodilator effect to overcome perioperative vasospasm of IMA.
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J. Cardiothorac. Vasc. Anesth. · Aug 2019
Observational StudyImpact of Preoperative Iron Deficiency on Blood Transfusion in Elective Cardiac Surgery.
To evaluate the incidence and consequences of preoperative iron deficiency in elective cardiac surgery. ⋯ Iron deficiency appears to be related to lower hemoglobin levels and more frequent transfusions in elective cardiac surgery. Assessing iron status preoperatively and correcting any iron deficiencies should be one of the numerous actions involved in patient blood management for such surgeries, with the aim of reducing morbidity associated with both anemia and transfusion.