Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Clinical TrialHeparin-bonded cardiopulmonary bypass circuits reduce cognitive dysfunction.
To determine the incidence of cerebral dysfunction in cardiac surgical patients exposed to heparin-bonded cardiopulmonary bypass (HB-CPB) versus nonheparin-bonded cardiopulmonary bypass (NH-CPB) circuits through neuropsychometric testing and to correlate these findings with markers of the systemic inflammatory response to CPB. ⋯ Patients undergoing cardiac surgery with CPB have less postoperative cognitive dysfunction during CPB when HB-CPB circuits are employed. Although there was a relationship, this finding did not correlate with decreased complement activation intraoperatively and activation of coagulation postoperatively.
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Clinical TrialMilrinone increases middle cerebral artery blood flow velocity after cardiopulmonary bypass.
To evaluate the effects of milrinone on middle cerebral artery blood flow velocity (Vmca) and pulsatility index (PI) during normocapnia and hyperventilation in adults after cardiopulmonary bypass (CPB). ⋯ The administration of milrinone increases cerebral blood flow after CPB most likely as a result of cerebral vasodilation. The response to hyperventilation seems to be partially preserved.
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialHypertonic saline (7.5%) decreases perioperative weight gain following cardiac surgery.
To compare the effects of 7.5% hypertonic saline (HS) and 0.9% normal saline (NS) on perioperative weight gain in cardiac surgical patients. ⋯ HS had an intense diuretic effect, which reduced intraoperative fluid retention. This effect was confirmed by the lesser increase in body weight measured on the first postoperative morning.
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Clinical TrialEpidural anesthesia and analgesia: effects on recovery from cardiac surgery.
To measure predefined clinical effects resulting from the use of epidural anesthesia and analgesia during and after cardiac surgery. ⋯ The clinical course of elective cardiac surgical patients who receive epidural anesthesia during surgery and epidural analgesia after surgery is comparable to that of patients managed with general anesthesia alone during surgery followed by parenteral opiate analgesia after surgery.