Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Jun 2001
Randomized Controlled Trial Clinical TrialTranexamic acid in aortic valve replacement.
To assess the relative efficacy of tranexamic acid compared with a control group to decrease bleeding and transfusion requirements in a uniform population undergoing aortic valve replacement. ⋯ Tranexamic acid reduces postoperative blood loss and transfusion requirements in elective aortic valve replacement.
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J. Cardiothorac. Vasc. Anesth. · Jun 2001
Randomized Controlled Trial Comparative Study Clinical TrialComparison of the effects of a cell saver and low-dose aprotinin on blood loss and homologous blood usage in patients undergoing valve surgery.
To compare 2 important techniques of blood conservation, use of a cell saver and low-dose aprotinin, in terms of blood loss and homologous blood usage in patients undergoing cardiac valve surgery. ⋯ Low-dose aprotinin and a cell saver are effective and comparable methods of blood conservation. Aprotinin helps by decreasing the postoperative drainage, and a cell saver helps by making the patient's own blood available for transfusion.
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J. Cardiothorac. Vasc. Anesth. · Jun 2001
Randomized Controlled Trial Comparative Study Clinical TrialComparison of the hemodynamic effects of milrinone with dobutamine in patients after cardiac surgery.
To compare the hemodynamic effects, efficacy, and safety of intravenous milrinone (M), 50 microg/kg during 10 minutes followed by 0.5 microg/kg/min, with intravenous dobutamine (D), 10 to 20 microg/kg/min, in patients with low cardiac output after cardiac surgery. ⋯ Milrinone and dobutamine are appropriate and comparable for the pharmacologic treatment of the low- output syndrome after cardiopulmonary bypass.