Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Jun 2012
Meta AnalysisFenoldopam and acute renal failure in cardiac surgery: a meta-analysis of randomized placebo-controlled trials.
Because at present no pharmacologic prevention or treatment of acute kidney injury seems to be available, the authors updated a meta-analysis to investigate the effects of fenoldopam in reducing acute kidney injury in patients undergoing cardiac surgery, focusing on randomized placebo-controlled studies only. ⋯ This analysis suggests that fenoldopam reduces acute kidney injury in patients undergoing cardiac surgery. Because the number of the enrolled patients was small and there was no effect on renal replacement therapy or survival, a large, multicenter, and appropriately powered trial is needed to confirm these promising results.
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J. Cardiothorac. Vasc. Anesth. · Feb 2012
Review Meta AnalysisRemifentanil in cardiac surgery: a meta-analysis of randomized controlled trials.
The authors conducted a review of randomized controlled trials to identify advantages in clinically relevant outcomes in patients undergoing cardiac surgery with remifentanil. ⋯ Remifentanil reduces cardiac troponin release, time of mechanical ventilation, and length of hospital stay in patients undergoing cardiac surgery.
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J. Cardiothorac. Vasc. Anesth. · Feb 2012
Meta AnalysisMilrinone and mortality in adult cardiac surgery: a meta-analysis.
The authors conducted a review of randomized studies to show whether there are any increases or decreases in survival when using milrinone in patients undergoing cardiac surgery. ⋯ This analysis suggests that milrinone might increase mortality in adult patients undergoing cardiac surgery. The effect was seen only in patients having an active inotropic drug for comparison and not in the placebo subgroup. Therefore, the question remains whether milrinone increased mortality or if the control inotropic drugs were more protective.
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J. Cardiothorac. Vasc. Anesth. · Feb 2012
Meta AnalysisAssociation between postoperative acute kidney injury and duration of cardiopulmonary bypass: a meta-analysis.
This meta-analysis examined the association between cardiopulmonary bypass (CPB) time and acute kidney injury (AKI). ⋯ Longer CPB times are associated with a higher risk of developing AKI-CPB, which, in turn, has a significant effect on overall mortality as reported by the individual studies.
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J. Cardiothorac. Vasc. Anesth. · Dec 2011
Review Meta AnalysisEndovascular stenting or carotid endarterectomy for treatment of carotid stenosis: a meta-analysis.
To compare carotid artery stenting with open carotid surgery for the treatment of symptomatic or asymptomatic carotid artery stenosis in terms of stroke, myocardial infarction, and death at 30 days. ⋯ Compared with stenting, carotid endarterectomy decreases the risk of stroke at 30 days, increases the risk of myocardial infarction, and does not affect the risk of death.