Journal of long-term effects of medical implants
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Extensive clinical investigations have demonstrated that double-gloves and blunt-tipped surgical needles dramatically reduced the risk of accidental injuries during surgery. During the last decade, double-glove hole puncture indication systems have been developed that reduce the clinical risk of accidental needlestick injuries as well as detect the presence of glove hole puncture in the presence of fluids. When the outer glove is punctured, the colored underglove becomes apparent through the translucent outer glove, necessitating glove removal, hand washing, and donning of another double-glove hole puncture Indicator system. ⋯ The taper point needle encountered the lowest puncture resistance forces in the five single gloves and the three double-glove systems. Blunting the sharp end of the taper point needle markedly increased its resistance to glove puncture in the five single gloves and five double-glove systems. The blunt-point surgical needle elicited the greatest needle penetration force in all of the single and double-glove systems.
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J Long Term Eff Med Implants · Jan 2002
ReviewModulation of immunosuppression by DNA transfer in transplantation.
Acute and chronic rejection of organ transplants continues to be the single most important source of allograft loss, and the induction of chronic immunosuppression leads to significant morbidity and mortality in transplants with long-term allograft function. Thus, induction of donor-specific unresponsiveness to organ allografts remains an elusive goal in clinical transplantation. ⋯ Despite the availability of powerful immunosuppressive drugs, allograft survival remains imperfect, and long-term therapy has often been accompanied by numerous side effects. Because the ultimate goal of transplant immunology is the development of a state of nonresponsiveness to the transplanted organ, gene transfer approaches may provide useful strategies for fulfillment of this goal.
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This guest editorial commentary outlines both the background and probable future developments of surgical tissue adhesive use in the United States and highlights the contributions made by the authors of this issue of the Journal of Long-Term Effects of Medical Implants. In addition, several issues specifically relevant to fibrin tissue adhesives in the United States are addressed. These include commercially available fibrin sealants and blood bank-produced products, as well as the proper nomenclature for such materials.
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J Long Term Eff Med Implants · Jan 1996
ReviewPotential toxicity of retrograde uterine passage of particulate matter.
Dusting powders are commonly used on surgical gloves, examination gloves, and condoms. In addition, they are used in diaphragms, sanitary napkins, and toiletries. ⋯ The toxicity of these dusting powders in the abdominal cavity can be divided into acute and chronic complications that may be life-threatening. The use of medical and surgical products without dusting powders is strongly recommended.