International journal of obstetric anesthesia
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Int J Obstet Anesth · Aug 2022
Case ReportsA description of the coagulopathy characteristics in amniotic fluid embolism: a case report.
Amniotic fluid embolism is frequently associated with coagulopathy. However, the exact nature and evolution of the bleeding disorder is incompletely understood. ⋯ We measured sequential levels of all individual clotting factors, thrombin generation, fibrinogen, and D-dimer levels over the course of the event, beginning shortly after the patient's initial collapse and during the subsequent resuscitation, to identify the specific abnormalities of coagulation from stored blood samples. A better understanding of amniotic fluid embolism and the associated coagulopathy is an important area of research to inform targeted treatment of the coagulopathy and improve outcomes for patients.
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Int J Obstet Anesth · Aug 2022
The effect of open-end versus closed-end epidural catheter design on injection pressure and dye diffusion under various programmed intermittent epidural delivery rates: an in vitro study.
Epidural catheter design may impact injection pressure and analgesic outcomes under programmed intermittent epidural bolus regimens. This in vitro study aimed to compare the injection pressure and dye diffusion between open-end and closed-end catheters at varying delivery rates. ⋯ At high delivery rates (>360 mL/h), the closed-end catheter had no advantages over the open-end catheters in diffusion distance or area. When using a close-ended catheter and high delivery rates, the peak pressure generated might trigger the occlusion alarm.