Indian journal of dental research : official publication of Indian Society for Dental Research
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Comparative Study
Comparison of cyanoacrylate and silk sutures on healing of oral wounds--an animal model study.
Cyanoacrylates are tissue adhesives used for closure of surgical wounds. N-butyl cyanoacrylate is a biocompatible tissue adhesive used for closure of surgical wounds. In the present study evaluation and comparison the healing of oral wounds was done when closed with N-butyl cyanoacrylate and silk sutures in a rabbit model. ⋯ At 7 days the histological picture correlated with the clinical findings and the amount of inflammation was less on the cyanoacrylate site. At 21 days both the sites appeared similar clinically and histologically. It is concluded that N-butyl cyanoacrylate tissue adhesive results in faster initial wound healing as compared to silk sutures and can be used for closure of oral wounds.
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In India, a number of fixed dose drug combinations of non-steroidal anti-inflammatory drugs (NSAID's) are available, often as over-the-counter products. These combinations are being prescribed too. Evidence for efficacy of NSIAD fixed dose combination is lacking. ⋯ Combining paracetamol with ibuprofen enhances analgesic/anti-inflammatory activity over their individual component but potentiation of analgesic activity of diclofenac was not seen when paracetamol was added to it.