Internal medicine
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Randomized Controlled Trial Multicenter Study
Non-superiority of Kakkonto, a Japanese herbal medicine, to a representative multiple cold medicine with respect to anti-aggravation effects on the common cold: a randomized controlled trial.
Kakkonto, a Japanese herbal medicine, is frequently used to treat the common cold not only with a physician's prescription, but also in self-medication situations. This study aimed to examine whether Kakkonto prevents the aggravation of cold symptoms if taken at an early stage of illness compared with a well-selected Western-style multiple cold medicine. ⋯ Kakkonto did not significantly prevent the progression of cold symptoms, even when prescribed at an early stage of the disease.
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Multicenter Study
A multicenter retrospective survey of poisoning after consumption of products containing synthetic chemicals in Japan.
We conducted a multicenter retrospective survey of patients poisoned by synthetic chemicals (SCs) in Japan. ⋯ Consuming products containing SCs can result in physical complications, including rhabdomyolysis, injuries, and physical or neuropsychiatric symptoms, which may require active interventions, such as respirator use or prolonged hospitalization.
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Multicenter Study
The prevalence and risk factors of microalbuminuria in hypertensive patients under current medical treatment.
A link between urinary albumin excretion and an increased incidence of cardiovascular mortality has already been demonstrated. However, the reported prevalence of microalbuminuria (MAU) in patients with hypertension is highly variable. We therefore aimed to conduct a cross-sectional multicenter study to investigate the prevalence of urinary albumin excretion in treated hypertensive patients in our current practice. ⋯ The present study showed that the prevalence of MAU among hypertensive patients was 42.8%, even in patients whose blood pressure was relatively well controlled. Additionally, the eGFR, systolic blood pressure, and HbA1c level are risk factors for the development of MAU. These findings suggest that a substantial number of hypertensive patients have MAU and highlight the importance of strictly controlling these factors to improve patient prognosis.
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Multicenter Study
Anxiety and depression in patients with Parkinson's disease.
To investigate the prevalence and clinical correlates of anxiety and depression in patients with Parkinson's disease (PD) and to examine the relationship between anxiety and depression and the quality of life (QOL). ⋯ These findings indicate that recognizing anxiety and depression in patients with PD is important, since both conditions are commonly observed in patients with PD and are similarly associated with the QOL, independent of motor severity.
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Review Case Reports Multicenter Study
Clinical features of 10 patients with IgG4-related retroperitoneal fibrosis.
To elucidate the clinical characteristics of IgG4-related retroperitoneal fibrosis (RF). ⋯ IgG4-related RF has several clinical characteristic features. Our diagnostic criteria may be helpful in obtaining a correct diagnosis.