Acta paediatrica
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Randomized Controlled Trial
Effect of high-dose paracetamol on needle procedures in children with cancer--an RCT.
The aim was to investigate whether children experience less pain, fear and/or distress when they receive high-dose paracetamol compared with placebo, using a needle insertion in a subcutaneously implanted intravenous port as a model. ⋯ Paracetamol provides no additive effect in reducing pain, fear and distress when combined with topical anaesthesia in children undergoing port needle insertion.
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Randomized Controlled Trial
Oral sucrose and non-nutritive sucking goes some way to reducing pain during retinopathy of prematurity eye examinations.
To evaluate the efficacy of oral sucrose combined with non-nutritive sucking for reducing pain associated with retinopathy of prematurity screening. ⋯ Although sucrose combined with non-nutritive sucking modestly reduces pain scores during eye examinations, there is need to further studies to explore significant pain relief for infants undergoing retinopathy of prematurity screening.
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Randomized Controlled Trial Comparative Study
Comparison of heart rate and oxygen saturation measurements from Masimo and Nellcor pulse oximeters in newly born term infants.
To compare heart rate (HR) measurements from Masimo and Nellcor pulse oximeters (POs) against HR measured via a three lead electrocardiograph (ECG) (HRECG ). We also compared peripheral oxygen saturation (SpO2 ) measurements between Nellcor and Masimo oximeters. ⋯ Both oximeters accurately measure HR. There was good agreement between SpO2 measurements when SpO2 ≥70%. At lower SpO2 , agreement was poorer.
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Randomized Controlled Trial
Expressed breast milk for procedural pain in preterm neonates: a randomized, double-blind, placebo-controlled trial.
To determine whether expressed breast milk (milk) reduces procedural pain associated with heel lancing in preterm neonates. ⋯ Although milk did not significantly reduce crying time, our finding that pain scores were significantly lower in the milk group suggests that milk may reduce pain associated with heel lancing in preterm neonates.
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Randomized Controlled Trial
Nasopharyngeal suctioning does not produce a salivary cortisol reaction in preterm infants.
To investigate whether nasopharyngeal suctioning produces a physiological and behavioural stress reaction in preterm infants and if a possible reaction can be dampened by sweet solution. ⋯ In the present setting, nasopharyngeal suctioning was not stressful enough to increase salivary cortisol or pain score. Oral glucose did not alter salivary cortisol levels.