Acta paediatrica
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Randomized Controlled Trial Clinical Trial
Sustained pressure-controlled inflation or intermittent mandatory ventilation in preterm infants in the delivery room? A randomized, controlled trial on initial respiratory support via nasopharyngeal tube.
To prove the hypothesis that sustained pressure-controlled inflation compared to intermittent mandatory ventilation for lung recruitment via nasopharyngeal tube after delivery is more effective in reducing the rate of endotracheal intubation and mechanical ventilation in very preterm infants. ⋯ Sufficient spontaneous breathing within the first 48 h of life without endotracheal intubation and mechanical ventilation was achieved in about 30% with both methods of initial respiratory support.
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To describe use of vasopressin infusion for catecholamine-refractory septic shock in children. ⋯ Vasopressin appears to be useful in treatment of catecholamine-refractory septic shock in children.
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Multicenter Study
Is procalcitonin useful in early diagnosis of serious bacterial infections in children?
To compare diagnostic accuracy of procalcitonin for early diagnosis of serious bacterial infection (SBI) in children presenting with fever and no focus of infection. ⋯ For early diagnosis of SBI in children presenting with fever and no focus of infection, the diagnostic utility of procalcitonin is similar to the traditional markers infection and clinical scoring. While a low procalcitonin level cannot be used to exclude SBI in this population, a combination of PCT, CRP and WBC may be more useful in predicting SBI.
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Randomized Controlled Trial Comparative Study Clinical Trial
A randomized trial comparing oxygen delivery on intermittent positive pressure with nasal cannulae versus facial mask in neonatal primary resuscitation.
To compare, in a prospective clinical trial, oxygen delivery on intermittent positive pressure with nasal cannulae versus facial mask in primary resuscitation of the newborn with moderate asphyxia. ⋯ Oxygen delivery on intermittent positive pressure with nasal cannulae in primary resuscitation of the newborn with moderate asphyxia is a less aggressive and potentially advantageous alternative to the traditional oral route.
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The limit of viability is intensely debated. Newborns below 500 g birthweight are often small for gestational age with an increased risk of short- and long-term mortality and morbidity. The level of given neonatal care must be individualized. A long-term follow-up for newborns with extremely low birthweight is urgently needed.