Journal of assisted reproduction and genetics
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J. Assist. Reprod. Genet. · Aug 2014
Comparative StudyChromosome distribution of early miscarriages with present or absent embryos: female predominance.
The objective of this study is to compare the chromosomal distribution of early miscarriages with or without embryonic poles. ⋯ Chromosome distribution differs in miscarriages with or without embryonic poles. The ultrasound findings might offer different direction to determine the causes of early miscarriages. The higher female abortus rate may be associated with early selection.
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J. Assist. Reprod. Genet. · Jun 2014
Maternal non-Mendelian inheritance of a reduced lifespan? A hypothesis.
A negative correlation exists between advanced maternal age and reproduction. Current data suggest that this correlation is due to a decline in oocyte quality with respect to female age. Since a new individual is derived from the fusion of a single sperm and egg, we tested whether the quality of this material could influence the long-term physiological health of offspring, by examining whether a link between parental age and lifespan of offspring exists. ⋯ These data demonstrate that intrinsic and extrinsic factors influence the lifespan of children. Among intrinsic factors, mother's lifespan and age at gestation had a significant influence on the data. The influence of intrinsic factors remained significant despite a strong extrinsic influence. We suggest that the influence of the mother on the lifespan of offspring is due to extra-genomic factors.
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J. Assist. Reprod. Genet. · Jun 2013
Relationship between oxidative stress and clinical pregnancy in assisted reproductive technology treatment cycles.
To examine the relationship between serum total oxidant (TOS) and antioxidant (TAS) levels and clinical pregnancy in assisted reproductive technology (ART) cycles. ⋯ In ART cycles, women with a higher total antioxidant status prior to and after OPU and prior to and after ET have an increased probability of clinical pregnancy. Additionally; OSI before OPU was one of the most important determinants for clinical pregnancy, so the oxidant and antioxidant balance is as important as the antioxidant concentration alone.