Paediatric anaesthesia
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Paediatric anaesthesia · Apr 2013
Randomized Controlled TrialEffect of short-term propofol administration on pancreatic enzymes and lipid biochemistry in children between 1 month and 36 months.
Use of propofol in pediatric age group has been marred by reports of its adverse effects like hypertriglyceridemia and acute pancreatitis, although a causal relation has not yet been established. ⋯ We conclude that despite a small, transient increase in serum triglycerides and pancreatic enzymes, short-term propofol administration in recommended dosages in children of ASA status I and II aged between 1 month and 36 months does not produce any clinically significant effect on serum lipids and pancreatic enzymes.