Paediatric anaesthesia
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Paediatric anaesthesia · Mar 2014
Neurotoxicity of sedative and analgesia drugs in young infants with congenital heart disease: 4-year follow-up.
To determine whether sedation/analgesia drugs used before, during, and after infant cardiac surgery are associated with neurocognitive and functional outcomes. ⋯ Assessment of this cohort at kindergarten age found a small statistically significant association between days on chloral hydrate and PIQ, and benzodiazepine cumulative dose and lower VMI. No other association between sedation/analgesia drugs and outcomes was found.
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Paediatric anaesthesia · Mar 2014
Randomized Controlled TrialEffects of promethazine or dexamethasone pretreatment on mivacurium-induced histamine release in children.
To determine the effects of pretreatment with either promethazine or dexamethasone on mivacurium-induced histamine release in children. ⋯ Pretreatment with promethazine significantly decreased mivacurium-induced histamine release in children and provided stable hemodynamics during administration of anesthesia.
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Paediatric anaesthesia · Mar 2014
Hunger and thirst numeric rating scales are not valid estimates for gastric content volumes: a prospective investigation in healthy children.
A rating scale for thirst and hunger was evaluated as a noninvasive, simple and commonly available tool to estimate preanesthetic gastric volume, a surrogate parameter for the risk of perioperative pulmonary aspiration, in healthy volunteer school age children. ⋯ Hunger and thirst scores vary considerably inter- and intra-individually and cannot predict gastric volume, nor do they correlate with fasting times in school age children.
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Paediatric anaesthesia · Mar 2014
Case ReportsLipid resuscitation in pediatric patients - need for caution?
A 3-year-old child was successfully resuscitated following bupivacaine cardiotoxicity with 20% intravenous lipid emulsion (ILE). Large volume of ILE was used targeting clinically adequate perfusion. Subsequently, there were features of ventilation/perfusion (V/P) mismatch.