Medicina intensiva
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Glutamine is the most abundant amino acid in the human body and plays an important role in a number of metabolic pathways. Specifically, it is involved in amino acid and nucleotide synthesis, in the tricarboxylic acid cycle and in ureagenesis. Glutamine has been classified as a non-essential amino acid because the body can synthesize it, but under severe clinical conditions, the pool of glutamine is depleted and could be considered as conditionally essential. ⋯ Administration of supplemental glutamine by enteral or parenteral route has produced controversial results. Most of the studies published support the hypothesis that glutamine can change the morbidity-mortality of the critically ill patients. There are unresolved questions related to the dose of glutamine and the best way to administer it, and particularly the subgroups of patients who will really benefit from this treatment.
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Bronchoalveolar lavage is the most effective treatment of alveolar proteinosis. We describe a variant of the usual technique. In a clinical case, we performed bronchoalveolar lavage sequentially in both lungs, without needing to stop the technique after completing the lavage of the first lung, with significant clinical improvement of the patient (pulmonary compliance and saturation). ⋯ Lavage of both lungs permitted discharge to ward in less than 24 hours. The result at middle term was similar to the conventional technique. Lavage could be performed again on several occasions with the same clinical tolerance.