American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Apr 2011
Multicenter Study Clinical TrialImproving pregnancy drug warnings to promote patient comprehension.
We sought to evaluate the effectiveness of a pharmaceutical labeling strategy intended to improve comprehension of a teratogen warning. ⋯ In our study, a teratogen warning label that had easy-to-read messages with icons significantly improved comprehension.
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Am. J. Obstet. Gynecol. · Apr 2011
Comparative StudyNeonatal brachial plexus injury: comparison of incidence and antecedents between 2 decades.
We sought to compare the incidence and antecedents of neonatal brachial plexus injury (BPI) in 2 different 5-year epochs a decade apart following the introduction of specific staff training in the management of shoulder dystocia. ⋯ Despite training in the management of shoulder dystocia and a rising institutional cesarean section rate, the incidence of BPI has remained unchanged compared with 10 years earlier.
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Am. J. Obstet. Gynecol. · Mar 2011
General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.
We sought to investigate maternal and child functional MDR1 C3435T polymorphism, periconception medication, folic acid use, and the risk of a congenital heart defect (CHD) in the offspring. ⋯ Mothers carrying the MDR1 3435T allele, using medication without folic acid, are at nearly 3-fold increased risk for CHD in the offspring.
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Am. J. Obstet. Gynecol. · Jan 2011
Oxytocin exposure during labor among women with postpartum hemorrhage secondary to uterine atony.
We sought to determine if women with severe postpartum hemorrhage (PPH) secondary to uterine atony received greater amounts of oxytocin during labor compared to women without PPH. ⋯ Women with severe PPH secondary to uterine atony were exposed to significantly more oxytocin during labor compared to matched controls.
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Am. J. Obstet. Gynecol. · Jan 2011
Randomized Controlled TrialDoes midtrimester Nugent score or high vaginal pH predict gestational age at delivery in women at risk for recurrent preterm birth?
To estimate whether bacterial vaginosis, as defined by either Nugent score or vaginal pH, predicts gestational age at delivery in women at risk for recurrent preterm birth. ⋯ The presence of bacterial vaginosis at 16-21⁶(/)⁷ weeks does not predict gestational age at birth in women at risk for recurrent preterm birth.