American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Apr 1996
Multicenter StudyCongenital diaphragmatic hernia: can prenatal ultrasonography predict outcome?
We wanted to establish whether prenatal ultrasonography predicts postnatal outcome in congenital diaphragmatic hernia. ⋯ In the majority of cases of isolated left congenital diaphragmatic hernia the prognostic value of fetal ultrasonography is too low to alter perinatal management.
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Am. J. Obstet. Gynecol. · May 1995
Randomized Controlled Trial Multicenter Study Clinical TrialLow-dose aspirin in nulliparous women: safety of continuous epidural block and correlation between bleeding time and maternal-neonatal bleeding complications. National Institute of Child Health and Human Developmental Maternal-Fetal Medicine Network.
Our purpose was to determine the frequency and safety of the use of epidural anesthesia and the correlation between bleeding time and maternal-neonatal bleeding complications in a group of pregnant women who participated in a multicenter trial of low-dose aspirin in pregnancy. ⋯ In women assigned to low-dose aspirin there were no adverse effects related to epidural anesthesia. In spite of an increased bleeding time in a subset of pregnant women assigned to low-dose aspirin, maternal-neonatal bleeding complications were not increased.
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Am. J. Obstet. Gynecol. · Mar 1993
Multicenter StudyIncreased incidence of neonatal vitamin K deficiency resulting from maternal anticonvulsant therapy.
The null hypothesis of our study is that the incidence of vitamin K deficiency in mother-infant pairs exposed to anticonvulsant drugs is not higher than in controls. ⋯ The incidence of vitamin K deficiency is increased in neonates exposed to anticonvulsant drugs prenatally. Their mothers, however, are rarely vitamin K deficient.