American journal of obstetrics and gynecology
-
Am. J. Obstet. Gynecol. · Sep 1993
Stimulation and inhibition of N-methyl-D-aspartate receptors in rats: developing a seizure model.
The objective of this study was to develop an experimental rat hippocampal seizure model based on the stimulatory effects of N-methyl-D-aspartate and to determine the inhibitory effects of MK-801 on N-methyl-D-aspartate-induced seizures. ⋯ Intracranial injection of 20 micrograms of N-methyl-D-aspartate produced reliable hippocampal seizure activity without mortality. MK-801 at a dose of 1 mg/kg injected intraperitoneally had significant inhibitory effects on this seizure model.
-
A historic survey of the literature and nine recent examples of uterine packing for control of postpartum hemorrhage are presented. Once a frequently practiced art, intracavitary packing for the control of uterine postpartum bleeding became a lost skill to most physicians after the 1950s. Objections to the practice are presented through a review of the literature. ⋯ Whether used early or late in patient management, uterine packing for the control of postpartum hemorrhage is a safe, quick, and effective procedure.
-
Am. J. Obstet. Gynecol. · Aug 1993
A twenty-year retrospective analysis of the efficacy of epidural analgesia-anesthesia when administered and/or managed by obstetricians.
The purpose of this study was to retrospectively determine the safety and efficacy of epidural anesthesia when administered by obstetricians in a community hospital. ⋯ Over a 20-year period epidural analgesia or anesthesia has been an effective and safe procedure when performed and supervised by obstetricians-gynecologists in a community hospital.
-
Am. J. Obstet. Gynecol. · Jul 1993
Comparative StudyVariation in hysterectomy rates across small geographic areas of Massachusetts.
Our objective was to determine whether small-area variation in hysterectomy rates exists within Massachusetts and, if so, whether regions with persistently high or low rates can be identified. ⋯ Possible explanations for these rate variations include indigenous population factors, supply of health care resources, income, insurance coverage, methodological problems in data analysis, and variation in professional judgment with regard to the indication for hysterectomy. Only a combination of the study of local causes of high and low rates and the study of the clinical outcomes of different treatment decisions will allow physicians to develop an informed consensus on appropriate indications for surgery.
-
Am. J. Obstet. Gynecol. · Jul 1993
First-trimester transabdominal multifetal pregnancy reduction: a report of two hundred completed cases.
Multifetal pregnancy reduction has been proposed as a way to reduce the risk of preterm delivery in women who conceive three or more fetuses. This communication presents the outcome of 200 consecutive multifetal pregnancies in which reduction to a smaller number of fetuses was accomplished. ⋯ The incidence of intrauterine growth retardation was not increased over that anticipated in a population of twins.