European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
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Back pain is a major problem worldwide and is linked to intervertebral disc degeneration and Modic change. Several studies report growth of bacteria following extraction of degenerate discs at spine surgery. A pathophysiological role for infection in back pain has been proposed. ⋯ Evidence to date implicates C. acnes identified through culture, microscopy and sequencing, with some suggestion of diverse bacterial colonisation in the disc. This review found studies which used culture methods and conventional PCR for bacterial detection. Further agnostic investigation using newer methods should be undertaken.
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The effect of paraspinal muscles atrophy and fat infiltration (FI) on the complications of spinal surgery has not been established. ⋯ Strong evidence was found for an association between preoperative paraspinal muscle degeneration and multiple postoperative complications after lumbar surgery. However, the findings should be interpreted with caution due to the small quantity of the available literature and high heterogeneity among studies.
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The effect of paraspinal muscles atrophy and fat infiltration (FI) on the complications of spinal surgery has not been established. ⋯ Strong evidence was found for an association between preoperative paraspinal muscle degeneration and multiple postoperative complications after lumbar surgery. However, the findings should be interpreted with caution due to the small quantity of the available literature and high heterogeneity among studies.
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Review Meta Analysis
Conundrum in surgical management of three-column injuries in sub-axial cervical spine: a systematic review and meta-analysis.
Systematic Review and Meta-analysis. ⋯ Diagnostic: individual cross-sectional studies with the consistently applied reference standard and blinding.
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Review Meta Analysis
Conundrum in surgical management of three-column injuries in sub-axial cervical spine: a systematic review and meta-analysis.
Systematic Review and Meta-analysis. ⋯ Diagnostic: individual cross-sectional studies with the consistently applied reference standard and blinding.