European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
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Prognostic models play an important clinical role in the clinical management of neck pain disorders. No study has compared the performance of modern machine learning (ML) techniques, against more traditional regression techniques, when developing prognostic models in individuals with neck pain. ⋯ The improvement in prediction performance between ML and logistic regression methods in the present study, could be due to the potential greater nonlinearity between baseline predictors and clinical outcome. The benefit of machine learning in prognostic modelling may be dependent on factors like sample size, variable type, and disease investigated.
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The paraspinal muscles (PSM) are a key feature potentially related to low back pain (LBP), and their structure and composition can be quantified using MRI. Most commonly, quantifying PSM measures across individual muscles and individual spinal levels renders numerous separate metrics that are analyzed in isolation. However, comprehensive multivariate approaches would be more appropriate for analyzing the PSM within an individual. To establish and test these methods, we hypothesized that multivariate summaries of PSM MRI measures would associate with the presence of LBP symptoms (i.e., pain intensity). ⋯ Our analysis considers the spine as a multi-segmental unit as opposed to a series of discrete and isolated spine segments. Integrative and multivariate approaches can be used to distill large and complex imaging datasets thereby improving the clinical utility of MRI-based biomarkers, and providing metrics for further analytical goals, including phenotyping.
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To improve the performance of less experienced clinicians in the diagnosis of benign and malignant spinal fracture on MRI, we applied the ResNet50 algorithm to develop a decision support system. ⋯ Our deep learning-based model may provide information to assist less experienced clinicians in the diagnosis of spinal fractures on MRI. Other findings away from the vertebral body need to be considered to improve the model, and further investigation is required to generalize our findings to real-world settings.
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The majority of lumbar spine surgery referrals do not proceed to surgery. Early identification of surgical candidates in the referral process could expedite their care, whilst allowing timelier implementation of non-operative strategies for those who are unlikely to require surgery. By identifying clinical and imaging features associated with progression to surgery in the literature, we aimed to develop a machine learning model able to mirror surgical decision-making and calculate the chance of surgery based on the identified features. ⋯ Through use of machine learning techniques, we were able to model surgical decision-making with a high degree of accuracy. By demonstrating that the operating patterns of single centres can be modelled successfully, the potential for more targeted and tailored referrals becomes possible, reducing outpatient wait-list duration and increasing surgical conversion rates.
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Sagittal balance (SB) plays an important role in the surgical treatment of spinal disorders. The aim of this research study is to provide a detailed evaluation of a new, fully automated algorithm based on artificial intelligence (AI) for the determination of SB parameters on a large number of patients with and without instrumentation. ⋯ A new, fully automated algorithm that determines SB parameters has excellent reliability and agreement with human raters, particularly on preoperative full spine images. The presented solution will relieve physicians from time-consuming routine work of measuring SB parameters and allow the analysis of large databases efficiently.