Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
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Support Care Cancer · Jan 2014
Rest/activity rhythm is related to the coexistence of pain and sleep disturbance among advanced cancer patients with pain.
This study aimed to explore the relationships among pain, sleep disturbance, and circadian rhythms in advanced cancer patients. ⋯ The rest/activity rhythm influences the coexisting pain and sleep disturbances. Pain functions as a complete mediator in their relationship. Interventions that improve rest/activity rhythms may improve the management of pain and sleep disturbances in cancer patients.