Ocular immunology and inflammation
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Ocul. Immunol. Inflamm. · Aug 2020
Ocular Features and Associated Systemic Findings in SARS-CoV-2 Infection.
To describe the prevalence of ocular features among COVID-19 patients and their relationship with clinical data, inflammatory markers and respiratory support therapy (including CPAP); to investigate SARS-CoV-2 in ocular secretions of symptomatic patients. ⋯ Ocular features are not infrequent in COVID-19 patients, but the presence of SARS-CoV-2 in ocular secretions is low. Ocular manifestations in hospitalized COVID-19 patients can also be a consequence of respiratory support therapy. Prevention of possible transmission through ocular secretions is still recommended.
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To investigate the possibility of ocular involvement in the 2019-novel coronavirus infectious (2019-nCoV) and vital preventive measures in the field of ophthalmology. ⋯ Ophthalmologists have an essential role in guiding cross-infection control measures between patients and staff. Until a vaccine is created, public health strategies are likely the best weapons against this invisible enemy.
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Ocul. Immunol. Inflamm. · Jul 2020
Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients.
To report the presence of viral ribonucleic acid (RNA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human retina in deceased patients with confirmed novel coronavirus disease 2019 (COVID-19). ⋯ Viral RNA of SARS-CoV-2 is detectable in the retina of COVID-19 patients.
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Ocul. Immunol. Inflamm. · Jul 2020
Ocular Manifestations of Hospitalized Patients with COVID-19 in Northeast of Iran.
To evaluate ocular findings in patients with Coronavirus Disease 2019 (COVID-19) in the Northeast of Iran. ⋯ Ocular manifestation was observed in more than half of our COVID-19 patients. Hence, it seems important to involve ophthalmologist in the diagnosis and management of these patients.
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Ocul. Immunol. Inflamm. · Jul 2020
ReviewCOVID-19 and the Ocular Surface: A Review of Transmission and Manifestations.
The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached pandemic proportions within an unprecedented span of time. It is controversial whether the virus can be transmitted via tears and its ocular implications have not been widely studied. In this article, the current evidence related to ocular transmission and ocular manifestations is reviewed. ⋯ The exact pathophysiology of ocular transmission of the virus remains incompletely understood, although there is preliminary evidence of SARS-CoV-2 being detected in ocular secretions. The ocular tropism of the virus and its potential to cause localized ocular disease are worth considering.