Der Anaesthesist
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Randomized Controlled Trial Comparative Study Clinical Trial
[Cognitive and psychomotor performance following isoflurane, midazolam/alfentanil and propofol anesthesia. A comparative study].
Mental and psychomotor abilities are impaired to varying degrees after general anaesthesia. This has important implications for the time over which patients are monitored in the recovery room and for the discharge of outpatients after day surgery. The present study was undertaken to compare recovery and mental and psychomotor skills in the first 60 min following general anaesthesia with isoflurane, midazolam/alfentanil and propofol. ⋯ The results indicate that in operations of approximately 90 min duration the return of motor and mental abilities is faster following propofol anaesthesia. At 30 min after extubation following propofol anaesthesia patients had test results that allow their transfer from the recovery room, while it took 60 min for patients in the two other groups to reach the same levels of motor and mental function. This is important for the duration of monitoring in the recovery room and, especially, for day case anaesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
[Post spinal headache. Its incidence following the median and paramedian techniques].
A lack of uniform methodology used by different authors in the assessment of different puncture techniques in spinal anesthesia formed the basis of the current study, which compared under randomized conditions the incidence of post spinal headache after a median or paramedian (lateral) approach. MATERIALS AND METHODS. Two hundred and fifty ASA physical status II and III patients, aged 50-85 years, scheduled for transurethral prostate surgery under spinal anesthesia were investigated. ⋯ The results indicate that the incidence of post spinal headache is higher in younger patients when using the paramedian (lateral) approach. However, our findings suggest that the choice of lumbar puncture technique--median or paramedian--is of little importance in regard to post-puncture headache in elderly patients. The paramedian approach is especially useful when degenerative changes are encountered in the interspinous structures in elderly patients, when an ideal position is difficult to achieve.
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Randomized Controlled Trial Clinical Trial
[The incidence of post spinal headache in a group of young patients].
Post-dural puncture headache (PDPH) is a significant and well-known complication of procedures that perforate the dura mater, e.g., clinical spinal anaesthesia (SpA). The exact mechanisms leading to PDPH are still not completely understood, although several factors, particularly the patient's age, modulate the incidence. In young patients (20-30 years) previous studies reported high occurrences of PDPH in 6%-16% of cases [5, 8], decreasing the value and acceptance of SpA in this patient group. ⋯ DISCUSSION. In contrast to previous studies reporting a high incidence of PDPH (6%-16%) in young adults, we found, in a stringent investigation of a large number of comparable patients in a defined age group, a PDPH rate of 3.5% and a few other minor side effects together with good anaesthetic quality, intraoperative stability, and excellent patient acceptance. Although future studies are needed to further minimise SpA complications, we found SpA a safe anaesthetic technique in our well-defined patient group.
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Randomized Controlled Trial Comparative Study Clinical Trial
[The accuracy of 4 different oximeters for continuous monitoring of mixed venous oxygen saturation during abdominal aortic surgery].
Several systems for mixed-venous oximetry are now available. There are one three-wave-length system (Abbott) and three two-wave-length systems with (Spectramed) and without automatic correction for hemoglobin or hematocrit (Edwards). The purpose of this prospective randomized study was to compare the different systems and to examine the accuracy of continuous mixed-venous oximetry during abdominal aortic surgery. ⋯ Data sets were obtained at eight predetermined times. Hemoglobin was kept constant at +/- 1 g.dl-1. Continuous oximetry in comparison to in-vitro measurements yielded a correlation coefficient of r = 0.873 (P less than 0.0001) and a value of bias and precision (b +/- p) of -0.9 +/- 2.6% for the SAT-1, r = 0.815 (P less than or equal to 0.0001) and b +/- p = -2.2 +/- 2.5% for the SAT-2, r = 0.901 (P less than or equal to 0.0001) and b +/- p = 0.35 +/- 2.5% for the Hemopro2, and r = 0.920 (P less than or equal to 0.0001) and b +/- p = 0.1 +/- 1.8% for the Oximetrix 3, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
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Randomized Controlled Trial Clinical Trial
[Atropine in the premedication of patients at risk. Its effect on hemodynamics and salivation during intubation anesthesia using succinylcholine].
Should atropine be administered for premedication? This question continues to be controversial; in particular, the combined administration of atropine and succinylcholine has been investigated with conflicting results by numerous researchers. The present study was carried out to assess the effect of premedication with atropine on hemodynamic variables and salivation in patients assigned to ASA class II and III. METHODS. ⋯ No increase in heart rate occurred in the control groups during tracheal intubation. Neither i.m. nor i.v. atropine had any significant effect on blood pressure. Arrhythmias occurred in a few cases with both routes of administration; several instances of marked tachycardia were recorded.(ABSTRACT TRUNCATED AT 250 WORDS)